Francois Jacob (1920-2013)
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چکیده
François Jacob studied bacteria and bacteriophages at the Institut Pasteur in Paris, France, in the second half of the twentieth century. In 1965, Jacob won the Nobel Prize in Physiology or Medicine [3] with André M. Lwoff and Jacques L. Monod for their work on the genetic control of enzyme synthesis. Jacob studied how genes [4] control and regulate metabolic enzymes in the bacterium Escherichia coli [5] (E. coli) and in lysogenic bacterial systems. He contributed to theories of transcriptional gene regulation [6], the operon model, and the distinction between structural and regulatory genes [4]. Jacob also introduced the concept of bricolage (tinkering) in evolutionary biology.
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Francois Jacob (1920-2013)
I knew Francois Jacob only slightly and yet, ever since graduate school, he has been my constant companion. Hardly a week has gone by without my asking him what he would think of this or that result, this or that sentence in a paper, and so on. What he would have thought of this impertinence I cannot say, because I never really let him know—the discussion went on mostly in my head. And so on he...
متن کاملGenetic regulatory mechanisms in the synthesis of proteins.
Francois Jacob Born 1920 in Nancy, France. Completed M.D. degree (1947) at Faculty of Paris, and a obtained doctorate in Science (1954) at the Sorbonne. Joined Institute Pasteur as research assistant (1950), under Dr. André Lwoff. Appointed Laboratory Director (1956) and Head of Dept. of Cell Genetics (1960). Began collaboration with Monod (1958) at Institute Pasteur. In 1964 became a Professor...
متن کاملMolecular Biology Through Discovery
Last week we eavesdropped on a meeting March 1960 in Sydney Brenner's apartment, in which Francois Jacob recounted recent results from Institut Pasteur. It was called Part I (Crick's Story), because I envisioned three parts: Part I. The world as seen through the eyes of Francis Crick, focusing on his view of an article by Belozersky and Spirin Part II. The world as seen through the eyes of Fran...
متن کاملFrançois Jacob (1920–2013)
“Plus que jamais, la recherche me paraissait s’identifier à la nature humaine. En exprimer l’appétit, le désir de vivre. C’était bien le meilleur moyen trouvé par l’homme de braver le chaos de l’univers. De dominer la mort.” (More than ever, scientific research seemed to me to be intrinsic to human nature. It expressed the hunger, the desire to live. It has, in fact, been the best means found b...
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